THE CHANGE OF LIPID METABOLISM OF PLACENTA BY PREGNANT WOMEN WITH PREECLAMPSIA

Tyurina Elena Pavlovna, Candidate of medical sciences, associate professor, sub-department of obstetrics and gynecology, Mordovia State University named after N. P. Ogaryov (Saransk), vap.61@yandex.ru
Kotlova Elena Vladimirovna, obstetrician, Municipal Maternity Hospital № 2 (Saransk), vap.61@yandex.ru
Vlasov Aleksey Petrovich, Doctor of medical sciences, professor, head of sub-department of faculty surgery, Mordovia State University named after N. P. Ogaryov (Saransk), vap.61@yandex.ru
Ledyaykina Lyudmila Viktorovna, Candidate of medical sciences, associate professor, sub-department of pediatry, Mordovia State University named after N. P. Ogaryov (Saransk), vap.61@yandex.ru
Gordeeva Yulia Vladimirovna, Student, Mordovia State University named after N. P. Ogaryov (Saransk), vap.61@yandex.ru

618.3-008.6:612.118.24

The authors have ascertained that at pregnants with hestosis in tissue structures of placentas there appear evident disorders in lipid metabolism. In pathogenesis of such disorders intensification of lipoperoxidation processes as well as activation of phospholipase A2 are of significant importance. Changes of the lipid metabolism as a display of membranodestabilization phenomenons in placenta are important pathogenetic factors of uterus-placenta insufficiency and, as a consequence, intrauterine suffering of foetus.

hestosis, placenta, lipids, peroxide oxidation of lipids.